Light microscopy allows scientists to visualize cells clearly under high magnification. While the cells can be seen clearly, there are some things that can’t be determined using this method, such as changes to the genetic material within the cells.
Researchers from the Broad Institute in Massachusetts believe they have discovered a new method; DNA microscopy. Unlike traditional methods, this new approach allows researchers to distinguish between genetic differences in cell types, which may be the result of cancer.
The team used chemical reactions to map the interior of cells and show where everything is located. This approach allowed the team to capture spatial information and genetic information about the cells at the same time. A computer program is able to collate this information and create images of the cells in a way never done before.
This new technique may allow future researchers to visualize cells with less expensive, and less specialized equipment. It would also allow researchers to process a larger number of samples than can be done with traditional methods.
Source: NY Times
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