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    • Genomics and Society
  • YEAR
    • 2017
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sector_ico_Health_trans Human Health
PathOGiST: Calibrated multi-criterion genomic analysis for public heal...

Public health agencies protect the population from infectious diseases by monitoring disease-causing agents (pathogens) and intervening in disease outbreaks. Without these concerte...

May 25, 2021
sector_ico_Health_trans Human Health
Empirical and Philosophical Analysis of Ethical Issues in the use of W...

Advancements in whole genome sequencing (WGS) technology have dramatically changed public health surveillance and outbreak investigations, allowing for accurate reconstruction of d...

May 25, 2021
sector_ico_Health_trans Human Health
Programmatic research to understand how modifiable environmental facto...

Asthma typically begins in childhood and lasts throughout life.  It is the leading cause of absenteeism from school and accounts for more than 30% of Canadian health care bill...

May 25, 2021
Data and Technology
Bioinformatics...

The bioinformatics platform at Canada's Michael Smith Genome Sciences Centre (GSC) is at the forefront of genomics research and collaboration. It has made seminal contributions...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
BeeCSI: ‘omic tools for assessing bee health...

Honey bees are crucial to agriculture and contribute up to $5.5 billion annually to the Canadian economy by pollinating valuable Canadian crops. However, the health of honey bees h...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Integrating genomic approaches to improve dairy cattle resilience: A c...

Dairy is one of Canada's most important industries, contributing roughly $19 billion to the country's GDP in 2025. As climate change and shifting consumer expecta...

May 25, 2021
sector_ico_Energy_trans Energy
The KetoBrick Platform: Biosynthesis of value-added chemicals from pho...

Emissions from industrial operations such as heat and power plants, natural gas production and chemical plants account for a significant portion of CO2 emissions in British Columbi...

May 25, 2021
sector_ico_Forestry_trans Forestry
Biological upgrading of lignin in black liquor...

BC pulp and paper industry needs innovative technologies to remain competitive and sustainable. A large decline in the demand for newsprint and other traditional paper products, as...

May 25, 2021
sector_ico_Health_trans Human Health
Quantifying the value of genomics-driven healthcare for children with ...

Approximately 500,000 Canadian children are classified as having a rare disease. Rare diseases are often complex, life-threatening, or chronically debilitating and over 80% of rare...

May 25, 2021
sector_ico_Fisheries_trans Fisheries and Aquaculture
Tracking Fish Health in the Nass River Watershed to Alleviate Mining A...

The fisheries and mining industries in British Columbia contribute approximately $1.2 and $8.8 billion respectively to the BC economy. The development of the Kerr-Sulphurets-Mitche...

May 25, 2021
sector_ico_Forestry_trans Forestry
Valorization of pulp & paper residues as slow-release nutrient am...

Industries in the natural resource sectors such as forestry, pulp and paper, and mining support the livelihoods of many Canadian communities and are important to Canada’s eco...

May 25, 2021
sector_ico_Health_trans Human Health
Characterization and analysis of amphibian host defence peptides as po...

Antibiotic resistance is a serious global problem. The World Health Organization has called the spread of resistant strains “the greatest and most urgent global risk, requiri...

May 25, 2021
sector_ico_Health_trans Human Health
GNOmics: Graphs ‘N’ Omics...

The reduced cost and increased quality of DNA sequencing technology, coupled with an ever-expanding collection of experimental results, allows for the regular sequencing of individ...

May 25, 2021
sector_ico_Fisheries_trans Fisheries and Aquaculture
Genomic Basis of Variation in Hypoxia Tolerance in Atlantic Salmon...

Aquaculture is an important industry in British Columbia: farm-raised Atlantic salmon contributes more than $728.6 million (landed value in 2017) annually to the BC economy. With i...

May 25, 2021
sector_ico_Health_trans Human Health
Indigenous Peoples and Genomics: Starting a conversation...

The human genome is the name for the entire sequence of DNA that guides the functioning of our bodies from conception to old age. When something goes wrong with our body, it can be...

May 25, 2021
sector_ico_Health_trans Human Health
Citizens’ preferences for next generation sequencing technologie...

Precision medicine uses information about a patient’s genomic profile to better prevent, treat, and predict disease course. New precision medicine technologies provide a larg...

May 25, 2021
sector_ico_Fisheries_trans Fisheries and Aquaculture
Atlas of genetic variation for climate change in chinook salmon...

Wild Pacific salmon in British Columbia (BC) is an important food source supporting commercial and recreational fisheries, and for First Nations they play a significant cultural, s...

May 25, 2021
sector_ico_Health_trans Human Health
Canadian Epigenetics, Environment and Health Research Consortium Netwo...

The DNA that makes up the genome (the collection of all the DNA in your cell) is tagged with various chemical marks that are attached either directly to the DNA or to its packaging...

May 25, 2021
sector_ico_Health_trans Human Health
OnTarget: Big Data Informed Software for the Design of cis-Regulatory ...

All cells of the human body have the same DNA sequences (genes) that “code” for the body’s entire diversity of cell types, from blood to brain, liver, muscle and ...

May 25, 2021
sector_ico_Health_trans Human Health
Precision Medicine CanPREVENT AMR- Applying Precision Medicine Technol...

The Canadian kidney transplant system has traditionally relied on list-based and geographic criteria to allocate organs, despite compelling evidence that genetic human le...

May 25, 2021
sector_ico_Environment_trans Environment
Bacterial Source Tracking to improve the health of two urban streams i...

The City of Vernon is challenged by degradation of its urban streams due to fecal contamination of surface water used for drinking and recreation. Current testing practices, such a...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Genomic Analysis of Wetland Sediment as a Tool for Avian Influenza Sur...

Avian Influenza (AI) is a viral disease that can cause significant morbidity and mortality in domestic poultry. AI outbreaks, and associated eradication efforts, have negative impa...

May 25, 2021
sector_ico_Health_trans Human Health
Implementing Genomics in the Neonatal Period...

The neonatal intensive care unit (NICU) at BC Women’s Hospital + Health Centre cares for approximately 1,200 premature or ill infants annually. Many have underlying genetic d...

May 25, 2021
sector_ico_Health_trans Human Health
Modeling and Therapeutic Targeting of the Clinical and Genetic Diversi...

Glioblastoma (GBM) is a deadly brain cancer that has eluded major treatment advances. New therapies for GBM are needed, however there is no consensus on how best to find them. The ...

May 25, 2021
sector_ico_Health_trans Human Health
GEL-GBC Rare Disease Pilot Study...

More than 80 per cent of the 7000 known rare diseases are genetic in origin. Genetic disorders of children are individually rare but collectively frequent, affecting the lives of a...

May 25, 2021
sector_ico_Forestry_trans Forestry
Connecting Genomics with First Nations values and interests- Developme...

This project was a collaborative initiative that developed original multimedia online educational materials tailored to the British Columbia (BC) high school science curriculum on ...

May 25, 2021
sector_ico_Health_trans Human Health
Clinical Assessment of the Utility of Sequencing and Evaluation as a S...

The BC Provincial Health Services Authority (PHSA), introduced a 3-year pilot program [the Clinical Assessment of the Utility of Sequencing and Evaluation as a Service (CAUSES) Cli...

May 25, 2021
sector_ico_Energy_trans Energy
Microbial community structure and dynamics associated with controlled ...

One of the pillars of British Columbia’s bioenergy strategy requires the use of blended biofuels including ethanol, methanol and biodiesel. Despite the promise of using blend...

May 25, 2021
sector_ico_Environment_trans Environment
Subsurface microbiome responses to fugitive natural gas...

Unconventional natural gas resource development risks releasing fugitive gas into groundwater and/or the atmosphere due to wellbore integrity failure. These leaks may affect ground...

May 25, 2021
sector_ico_Environment_trans Environment
Understanding the algal microbiomes living on alpine snowfields in sou...

Snow in alpine and polar regions takes on a pinkish hue during the summertime. This “watermelon snow” or “red snow" is caused by blooms of microscopic algae ...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Genomics of viruses and microbial symbionts of spotted wing Drosophila...

Spotted wing Drosophila (SWD), an invasive insect pest, lays its eggs in berries and other small fruits causing them to rot. In BC, ~25% of SWD harbor an intracellular symbiotic ba...

May 25, 2021
Data and Technology
AnnoVis- Annotation and visualization of de novo genome and transcript...

Establishing a fundamental understanding of the specific molecular biology of a species begins with reconstructing its genome (DNA) and transcriptome (RNA). Assembling the large vo...

May 25, 2021
sector_ico_Environment_trans Environment
Global scale metabolic pathway reconstruction from environmental genom...

For more than 3.5 billion years, microorganisms have been the dominant form of life on Earth, mediating global fluxes of matter and energy. Over the past decade, high-throughput om...

May 25, 2021
Data and Technology
Bioinformatics Tools to Enable Federated, Real Time Genomic Epidemiolo...

Infectious diseases can devastate both animal and human lives, damage economies and paralyze trade. The One Health approach recognizes that the health of humans, animals and the en...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Examining Public Beliefs about the Ethics of Genetically Modifying Liv...

This project aimed to understand societal concerns around the acceptability of Genetically Modified (GM) technology applied to animal agriculture, and how these conc...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
The Regulatory Environment for Gene-Edited Crops: A Cross-National Com...

Recently, claims have arisen that “GM 2.0” has arrived, bringing a suite of new Gene Editing (GE) techniques that supercharge existing and well-known genetic modificati...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Understanding the Perceived Risks and Benefits of Agricultural Applica...

Our food system faces major challenges—in particular, adapting to climate change and feeding a growing global population. Recently, gene editing (GE) technologies have made i...

May 25, 2021
sector_ico_Health_trans Human Health
Biomarkers for Crossing the Translational Divide in Acute Spinal Cord ...

There are currently no neuro-restorative treatments for acute spinal cord injury (SCI). The few promising experimental therapies for SCI that have been translated to humans have fa...

May 25, 2021
sector_ico_Health_trans Human Health
A chemo-affinity toolkit for methylation proteomics...

Protein methylation is a post-translational modification process involving the addition of methyl groups to a region of the protein.  The process plays an important role in pr...

May 25, 2021
sector_ico_Health_trans Human Health
Integrating Pediatric Pharmacogenomic Testing into the Canadian Health...

Pharmacogenomics is the study of how an individual’s genes affect their ability to respond to medications (drugs). This project has developed and implemented pharmacogenomic ...

May 25, 2021
sector_ico_Health_trans Human Health
Centre for Epigenome Mapping Technologies...

This national partnership with CIHR aims to support leading edge research on the role of DNA and environment interactions in human health and disease. Epigenetics is a field that i...

May 25, 2021
sector_ico_Health_trans Human Health
An Epigenomic Data Coordination Centre for Canada...

This national partnership with the Canadian Institutes of Health Research (CIHR) aims to support leading edge research on the role of DNA and environment interactions in human heal...

May 25, 2021
sector_ico_Health_trans Human Health
Preclincal development of a disease modifying small molecule therapy f...

No medications exist that can stop or even slow the progression for Alzheimer Disease (AD). The two pathological hallmarks of AD are protein aggregates deposited in the brain that ...

May 25, 2021
sector_ico_Environment_trans Environment
Synthetic Biology Solutions for Detoxification of Oil Sands Process Af...

Oil sands mining industry generates large volumes of Oil Sand Process-affected Water (OSPW) consisting of persistent organic pollutants, such as Naphthenic Acids (NA). Treatment of...

May 25, 2021
sector_ico_Health_trans Human Health
PEGASUS-2 – PErsonalized Genomics for prenatal Abnormalities Scr...

The discovery that fetal DNA is present in the mother’s blood during pregnancy has led to the development of a genomics-based maternal blood test called NIPS (non-invasive pr...

May 25, 2021
sector_ico_Health_trans Human Health
Detection and Tracking of Carbapenemase-producing organisms (CPOs)...

Antibiotics are effective agents in the fight against microbial infections. However, their long term use, as well as the misuse, has led to rapid evolution and dissemination of ant...

May 25, 2021
sector_ico_Health_trans Human Health
Development, validation and worldwide dissemination of a standard and ...

More than a quarter of a million Canadians, including ~80,000 BC residents, are living with Hepatitis C and approximately 5,000 new infections occur annually across Canada. Chronic...

May 25, 2021
sector_ico_Health_trans Human Health
Viral and Human Genetic Predictors of Response to HIV Therapies...

The HIV drug "cocktail" has transformed AIDS from a fatal disease to a manageable condition. Unfortunately, HIV can become resistant to these drugs, leading to the development of f...

May 25, 2021
sector_ico_Health_trans Human Health
Automated Tumor Pathology...

To use genomics to aid in cancer treatment, a normal sample of the patients DNA is compared to the DNA from the cancerous tumour. This is&nb...

May 25, 2021
sector_ico_Health_trans Human Health
Improving Diagnosis and Treatment of Catecholaminergic Polymorphic Ven...

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited condition characterized by abnormal heartbeat (arrhythmia) resulting in sudden cardiac death (SCD) for ...

May 25, 2021
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