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  • YEAR
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sector_ico_Health_trans Human Health
DeCIDE – Short for Designer Cellular Immuno-Engineering for Infectio...

Cell therapy is a rapidly evolving field with the potential to transform medicine, particularly in treating cancer and autoimmune diseases. It involves engineering healthy cells, e...

January 19, 2026
sector_ico_Agrifood_trans Agrifood
Identification of Seed-borne Pathogens Using Metabolomics...

Plant diseases pose a significant threat to global agriculture, resulting in annual crop yield losses exceeding $200 billion USD. Current methods for testing seeds during productio...

January 10, 2026
sector_ico_Environment_trans Environment
A New Paradigm for Pigment Production in Microbes...

The colourant industry is a major polluter globally, producing 20% of the world’s wastewater and consuming 800,000 tonnes of synthetic colourants annually. The discharge of c...

January 10, 2026
sector_ico_Agrifood_trans Agrifood
Advancing Bioengineered Production and Commercialization of the Novel ...

Type 2 diabetes (T2D) is a defining disease of the 21st century; affecting over 500 million people worldwide and predicted to increase to 1.3 billion by 2050. Control of blood gluc...

January 10, 2026
sector_ico_Health_trans Human Health
Developing Topical Formulations of Natural, Plant-derived Granzyme B I...

Pressure injuries, also called pressure ulcers or bed sores, refer to damage or wounds in the skin caused by placing pressure on the skin, most often over bony areas of the bo...

December 06, 2025
sector_ico_Health_trans Human Health
Targeted Self-amplifying Nucleic Acid Vaccine Design for Bladder Cance...

Bladder cancer is the fifth most common cancer in Canada. Approximately 37 people are diagnosed a day and bladder cancer is the most expensive cancer to treat [1]. Despite advancem...

December 06, 2025
sector_ico_Agrifood_trans Agrifood
HEAT-GRAPE: Identification of transcripts and metabolites involved in ...

Wine is critical to British Columbia’s (BC) agricultural economy, generating over $3.75 billion in economic activity and supporting 14,272 jobs. However, climate change is ch...

December 06, 2025
sector_ico_Fisheries_trans Fisheries and Aquaculture
Impact of increased ocean temperature on Aeromonas salmonicida virulen...

Ocean temperatures are increasing and fish are especially susceptible to this warming as they are cold-blooded, and their body temperature conforms to the temperature of their envi...

December 06, 2025
sector_ico_Health_trans Human Health
The Impact of Climate Change-Related Pollutants on Lung Cell Omics...

Increases in the severity and frequency of wildfires, atmospheric carbon dioxide and higher air temperatures result in an increase of airborne allergens (aeroallergens) and prolong...

December 06, 2025
sector_ico_Fisheries_trans Fisheries and Aquaculture
The Effect of Microbiome on Adaptation to Global Warming and Survival:...

The human microbiome plays an integral role in shaping our biology with a similar number of bacterial (38 trillion) and human (30 trillion) cells. These microorganisms are not pass...

December 06, 2025
sector_ico_Health_trans Human Health
Prenatal Exposure to Wildfire Disasters and their Association with Ear...

Wildfires are becoming more frequent and severe in British Columbia and beyond due to climate change. These events are linked to serious risks to our respiratory health and can dis...

December 06, 2025
sector_ico_Health_trans Human Health
COPD-induced innate immune memory: an amplifier of inflammatory respon...

Over 2 million Canadians are affected by chronic obstructive pulmonary disease (COPD), an ongoing lung condition characterized by trouble breathing, coughing, and wheezing. It is t...

December 06, 2025
sector_ico_Fisheries_trans Fisheries and Aquaculture
Climate Effects on Zooplankton Resilience in Changing Environments...

Global climate warming significantly alters marine ecosystems by changing species distribution, body size, reproduction rates, mortality rates and the nutritional values of prey fo...

December 06, 2025
sector_ico_Fisheries_trans Fisheries and Aquaculture
Applied Genomics of River-type Sockeye Salmon to Inform Climate-resili...

Wild salmon are under great stress from climate change, making it vital to find new ways to help them adapt and remain resilient. Genomic methods can discover the diversity that gi...

December 06, 2025
sector_ico_Health_trans Human Health
A Predictive Test for Myeloid Cancer Therapy...

MDS (Myelodisplastic syndromes) and AML (acute myeloid leukemia) are aggressive forms of blood cancers with poor survival rates. Younger patients with these cancers are usually giv...

December 06, 2025
Data and Technology
Efficient and Resilient Genome Active Data Archiving...

In today’s rapidly advancing world of human health genomics, unprecedented volumes of patient sequence data are being generated, requiring more energy, space, and resources t...

December 06, 2025
sector_ico_Agrifood_trans Agrifood
Genomic and Sequence-Based Characterization of the Host-Pathogen Inter...

Legal cannabis (Cannabis sativa L.) production in Canada, and in many U.S. states where cultivation is legal, for plants with high tetrahydrocannabinol (THC) levels has rapidly exp...

December 06, 2025
sector_ico_Fisheries_trans Fisheries and Aquaculture
Epigenetic Biomarkers and Assays to Support Chinook Salmon Enhancement...

Chinook salmon are an iconic species with significant economic, cultural and ecological importance in British Columbia. Fisheries and Oceans Canada (FOC) plays a crucial role in ma...

December 06, 2025
sector_ico_Health_trans Human Health
Deciphering the transcription factor code (TFcode) of human cell diffe...

STEMCELL Technologies is a Canadian biotechnology company based in Vancouver, British Columbia, that supplies laboratory reagents to scientists researching stem cells worldwide. Hu...

December 06, 2025
sector_ico_Health_trans Human Health
Development of a human in vitro transplant model for studying ABO bloo...

Organ transplantation is a life-saving therapy, but the need for a compatible match between donor and recipient often leads to long waiting times. In Canada, over 4500 patients, in...

December 06, 2025
sector_ico_Agrifood_trans Agrifood
Mechanisms and resistance pathways of existing and future acaricides a...

Honeybees play an indispensable role in our food production, not only providing honey but also pollinating a diverse array of crops. They are essential for sustaining agriculture a...

December 06, 2025
sector_ico_Agrifood_trans Agrifood
Climate–Smart Data Collaboration Centre (CSDCC)...

Genome Canada’s Climate-Smart Agriculture and Food Systems (CSAFS) Initiative aims to reduce greenhouse gas emissions and the carbon footprint of Canada’s food producti...

December 05, 2025
sector_ico_Environment_trans Environment
BIOSCAN-CANADA...

The Global Risks Report 2020 from the World Economic Forum ranked biodiversity loss a top five threat facing humanity. To address this risk, we need to understand how species inter...

December 05, 2025
sector_ico_Health_trans Human Health
A Pathogen-ready Arsenal of Next Generation Lipid Nanoparticle (LNP) M...

Ribonucleic acid (RNA) based genetic medicines are a promising way to treat many diseases as these medicines can be highly personalized. However, there remain challenges to their d...

December 04, 2025
sector_ico_Health_trans Human Health
Microbiota for Pandemic Interventions and Exploration (MiPEx)...

Misuse of antibiotics is causing an emerging threat to global public health due to the development of antimicrobial resistance (AMR). This poses a high risk of fatality in patients...

December 04, 2025
sector_ico_Health_trans Human Health
Improving mental healthcare in BC: A well-being gathering to understan...

Depression is very common. In Canada, more than 1 in 10 people will experience major depression in their lifetime, with even higher rates among Indigenous Peoples. While there are ...

December 04, 2025
sector_ico_Health_trans Human Health
Closing GAPS: Genomic Approach to Preventing Spread of Healthcare-Asso...

Multi-drug resistant infections are a growing global health crisis, responsible for millions of deaths worldwide. In Canada alone, an estimated 14,000 deaths in 2018 were linked to...

December 04, 2025
sector_ico_Health_trans Human Health
Mainstreaming Genetic Testing for Non-Ischemic Cardiomyopathy in Weste...

Heart muscle disorders are a leading cause of heart failure, a life-threatening condition that can lead to dangerous abnormal heart rhythms (arrhythmia) and fluid buildup in the bo...

December 04, 2025
sector_ico_Health_trans Human Health
Pharmacogenetics Data Standardization to Enhance Findability, Accessib...

Pharmacogenetics (PGx) testing enables health-care providers to personalize medications and dosages based on a patient’s genetic profile, improving treatment effectiveness an...

December 04, 2025
sector_ico_Health_trans Human Health
Development and testing of an at-home lung cancer screening test...

Lung cancer remains one of the deadliest cancers in Canada, with nearly 50% of cases diagnosed at Stage IV, where survival rates are extremely low. Early detection is critical to i...

December 04, 2025
sector_ico_Health_trans Human Health
Overcoming Barriers for Rapid Adoption of Donor-Derived Cell-Free DNA ...

Kidney transplantation is the most effective treatment for kidney failure, yet more than 25% of kidney transplants in Canada fail within 10 years due to rejection or other injuries...

December 04, 2025
sector_ico_Health_trans Human Health
Pediatric Innovations in Genomics: Let Everyone be Tested...

This project aims to develop, validate and implement an expanded pharmacogenetic test panel to predict the risk of seven severe chemotherapy-induced adverse drug reactions (ADRs) i...

December 04, 2025
sector_ico_Health_trans Human Health
Silent Genomes: Building a Sustainable Path to Genetic/Genomic Care fo...

In Canada, genomic sequencing to diagnose genetic conditions is a common practice across many medical specialties, including, but not limited to, clinical genetics, cardiology, imm...

December 04, 2025
sector_ico_Health_trans Human Health
Pharmacogenomic testing for people with major depression: A study of i...

In Canada, more than 1-in-10 people will suffer a form of major depression at some point in their lives. Drug therapy is often used to treat major depressive disorder (MDD) and the...

December 04, 2025
sector_ico_Health_trans Human Health
“New Product Launch – Diffusion of Innovations” Overcoming B...

Simply promoting new medical tests by relying on the message “science says this is good for you” approach often fails to persuade everyone. This project will test promo...

November 18, 2025
sector_ico_Environment_trans Environment
eDNA Explorer Canada: Upscaling eDNA Explorer to Enable Effective Biod...

Environmental DNA (eDNA) refers to genetic material shed by organisms—animals, plants, fungi and microbes—into their surroundings. By analyzing eDNA, we can identify sp...

November 18, 2025
Data and Technology sector_ico_Health_trans Human Health
Platform for Regulatory Science, Innovation, and Equitable Health Syst...

Canada’s life sciences sector is turning research into solutions that address health threats. However, there is a central challenge that needs to be overcome; existing practi...

November 17, 2025
sector_ico_Health_trans Human Health
Parent-of-Origin-Aware Genomic Analysis: A Mixed Methods Evaluation to...

About 1 in 200 Canadians carry a mutation in high-risk cancer genes like BRCA1 or BRCA2, but only about 10% of them know it. These hereditary cancer syndromes (HCS) can affect mult...

November 17, 2025
sector_ico_Health_trans Human Health
Development of 3D-printed Cardiac Organoids for -Omics Applied to Pers...

Axolotl Biosciences, a Canadian start-up with revenue-generating products, has identified a new commercial opportunity through a comprehensive market assessment. Building on its ex...

November 17, 2025
sector_ico_Health_trans Human Health
Longitudinal, Deep-Phenotyped Pediatric Databank of Medical and Drug T...

Many children experience serious side effects from medications, but because pediatric diseases like cancer are rare, it is difficult to gather enough data to understand why. Over t...

November 17, 2025
sector_ico_Health_trans Human Health
Multi-Omics and Sonography to Advance Integrated Cardiac Care...

Cardiovascular disease remains one of the leading causes of death in Canada, but current methods for predicting risk often fail to account for diverse populations. Many genetic stu...

November 17, 2025
sector_ico_Health_trans Human Health
Population-based Testing for Hereditary Cancer Predisposition: Explora...

Some people inherit genes that put them at a much higher risk of developing cancer. For example, a young woman with a BRCA1 gene mutation has a 75% chance of developing breast canc...

September 24, 2025
sector_ico_Health_trans Human Health
Cancer Genomics – A multi-disciplinary approach to large-scale h...

Cancer kills one third of the Canadian population and millions of people are living with cancer. The goal of this project was to detect cancers at an early stage to increase the ch...

August 02, 2025
sector_ico_Health_trans Human Health
An LNP-mRNA brain Bioreactor strategy to treat neuronopathic Gaucher D...

An estimated 3.8 million Canadians live with a neurological condition, with a projected two-fold increase in this number by 2031. Brain disorders are often progressive, debilitatin...

August 01, 2025
sector_ico_Health_trans Human Health
Time for Plan B: In search for universal blood using B-to-H blood anti...

The ABO blood group system classifies blood into four groups: A, B, AB, and O. These groups are defined by specific sugar molecules, known as blood antigens, expressed on red blood...

August 01, 2025
Data and Technology sector_ico_Health_trans Human Health
Technologies and tools for next-generation oligonucleotide therapeutic...

Oligonucleotide therapeutics (ONTs) are a promising class of medicine that work by directly interacting with genetic material (DNA or RNA) to influence gene activity. This makes th...

August 01, 2025
Data and Technology sector_ico_Health_trans Human Health
Scaling Gene Synthesis 100-fold Using a Novel Multiplexed Assembly Pla...

Synthetic biology applies engineering principles to design novel DNA sequences based on natural templates. Researchers use these sequences to uncover how DNA encodes function and t...

August 01, 2025
sector_ico_Health_trans Human Health
Microbiota for Antimicrobial Resistance Exploration (MiAREx)...

Antimicrobial resistance (AMR) is a pressing global health challenge that is predicted to cause around 10 million deaths annually by 2050. Global overuse of antibiotics has caused ...

August 01, 2025
sector_ico_Environment_trans Environment
ChùNet, Enabling a Knowledge Sharing Network – Learning from Wa...

Chù (Water) is life. Water ecosystems can teach us about ourselves and the world around us. Humans, other life and viruses all shed their genetic material into water. By sam...

June 26, 2025
sector_ico_Environment_trans Environment
iMicroSeq: Integrated, Inclusive Resources Supporting Environmental Se...

Water is essential for all life and holds valuable information about the health of our communities and the environment. Modern methods have been developed to monitor water quality ...

June 26, 2025
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