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  • YEAR
    • 2017
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sector_ico_Forestry_trans Forestry
SYNBIOMICS: Functional genomics and techno-economic models for advance...

The SYNBIOMICS project aimed to advance sustainable bioproduct synthesis by reconstructing and upgrading abundant but underutilized woody biomass—cellulose, hemicellulose, an...

May 25, 2021
sector_ico_Forestry_trans Forestry
Spruce tree and spruce beetle genomics for response to a growing infes...

The recent spruce beetle outbreak in BC is larger than any previously recorded outbreak and has the potential to change forest ecosystems in BC. Increased spruce beetle activity ca...

May 25, 2021
sector_ico_Forestry_trans Forestry
Cedar Enhanced Durability and Resistance (CEDaR): Sustainability of Ca...

Canada’s $1.1B iconic western redcedar (WRC) export industry is facing a precipitous decline, as the durable and aesthetically appealing timber supply moves from old growth t...

May 25, 2021
sector_ico_Forestry_trans Forestry
CoAdapTree – Healthy trees for future climates...

This project aims to develop better reforestation options for high-value tree species such as Douglas fir and lodgepole pine, as well as western larch and jack pine trees. Genomic ...

May 25, 2021
sector_ico_Forestry_trans Forestry
BioSurveillance of Alien Forest Enemies (bioSAFE)...

Forests are a crucial part of Canada’s cultural, social and economic fabric. However, invasive alien species and diseases threaten our forests and cause potentially irreversi...

May 25, 2021
Data and Technology
The Metabolomics Innovation Centre (TMIC)...

The Metabolomics Innovation Centre (TMIC) was launched in 2011 as a Genome Canada Science and Technology Innovation Centre. TMIC now serves as Canada’s national metabolomics ...

May 25, 2021
sector_ico_Health_trans Human Health
Targeting the Synaptic Pathway in Neurodevelopmental and Psychiatric D...

Autism and schizophrenia affect over 1% of the population, and each has strong genetic associations with 60-90% heritability among twins. Recent research identified mutations in a ...

May 25, 2021
sector_ico_Health_trans Human Health
Locally produced brain insulin in memory and Alzheimer’s disease...

It is clear from population-level studies that there are important links between Alzheimer’s disease and obesity, altered fat metabolism, diabetes and insulin. The team demon...

May 25, 2021
sector_ico_Health_trans Human Health
Prevention of Healthcare Associated Infections in Bone Marrow Transpla...

Healthcare-associated infections (HAI) continue to burden patients and healthcare systems worldwide. Current environmental surveillance programs rely on culture-based methods to de...

May 25, 2021
sector_ico_Health_trans Human Health
Canadian ‘Rare Diseases: Models & Mechanisms’ Network...

Mutations in the human genome can cause rare diseases. In Canada, one in 12 people are affected by a rare disease — about two-thirds of them are children. Identifyin...

May 25, 2021
sector_ico_Health_trans Human Health
Reimagining genome browsing for the era of single cell genomics...

Human tumours develop through the accumulation of mutations in their DNA. Individual cells within a tumour can acquire different mutations, which may respond differently to therapy...

May 25, 2021
sector_ico_Forestry_trans Forestry
Protecting Canada’s Forests against Invasive Alien Species by Ne...

In 2016, the forest industry contributed over $23 billion to Canada’s nominal Gross Domestic Product.  As one of the most important manufacturing sectors, forestry made ...

May 25, 2021
sector_ico_Health_trans Human Health
Canadian National Transplant Research Program: Increasing Donation an...

Organ and bone marrow transplants are well-established treatments for patients with incurable medical conditions. However, major gaps and obstacles prevent transplantation from bei...

May 25, 2021
sector_ico_Health_trans Human Health
Development of Novel Biomarker Blood Tests for COPD...

Chronic Obstructive Pulmonary Disease (COPD) is a chronic, progressive disease that results in damaged lung airways, making it difficult to breathe.  Patients suffer “lu...

May 25, 2021
sector_ico_Health_trans Human Health
Immunogenomics Core...

The BC Cancer Agency's Cancer Immunotherapy Program aims to use genomic and related technologies to develop precise and potent immunotherapeutic strategies for cancer. To ...

May 25, 2021
sector_ico_Health_trans Human Health
Targeting Amyloid Propagation in Alzheimer Disease: Structures, Immuno...

Small aggregates of the protein amyloid-beta (A-beta), called oligomers, have been identified as being the primary cause of brain cell death in Alzheimer’s disease. The ...

May 25, 2021
sector_ico_Health_trans Human Health
Propagated protein misfolding of SOD1 in ALS: Exemplar for Neurodegene...

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive fatal disease that affects the nerve cells responsible for muscle movement. 30,000 individ...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Reference Genome Sequences for Apple and Sweet Cherry Licensing Enforc...

BC's interior tree fruit industry generates $130 million in wholesale revenue, contributes $900 million in economic activity, and directly employs 1,500 people annually. Ninety-fiv...

May 25, 2021
sector_ico_Environment_trans Environment
Climate change mitigation through algal bioproduction...

Microscopic algae hold tremendous potential for addressing societal challenges in a sustainable way. One such challenge is the environmental damage caused by abandoned mines. Water...

May 25, 2021
sector_ico_Health_trans Human Health
The vaginal microbiome project team. Characterizing the role of the va...

Advances in genome sequencing and bioinformatics have provided new tools to systematically investigate the human microbiome, and the opportunity to decipher the role that microbes ...

May 25, 2021
sector_ico_Energy_trans Energy
Genetic Engineering for Photosynthetic Proteins for Solar Energy...

Solar power is an abundant sustainable energy source: in a single hour, the sun irradiates enough energy to meet humanity's needs for an entire year. However, solar energy is curre...

May 25, 2021
Data and Technology
The Metabolomics Innovation Centre...

Metabolomics is a relatively new area of science that measures the thousands of small molecules in cells, tissues and organisms. While small, these molecules, also called metabolit...

May 25, 2021
Data and Technology
The Proteomics Centre (PC): An Integrated GIN Node for Comprehensive, ...

Proteomics is the study of proteins and their interactions. Studying what proteins are expressed and in what quantities is highly complex, but can provide sophisticated information...

May 25, 2021
Data and Technology
Methods and Technology Development at the Sequencing Platform at the B...

The sequencing platform at Canada’s Michael Smith Genome Sciences Centre (GSC) at the BC Cancer Agency has been delivering large-scale DNA sequencing data efficiently and rel...

May 25, 2021
sector_ico_Health_trans Human Health
Accelerating the development of a novel outer membrane protein based v...

Chlamydia trachomatis is the causative agent of one of the most widespread bacterial sexually transmitted diseases in the world causing an estimated 92 million infections per years...

May 25, 2021
Data and Technology
BC Cancer Agency Genome Sciences Centre Genomics Technology Platform...

The sequencing analysis platform at Canada's Michael Smith Genome Sciences Centre (GSC) is at the forefront of international genomics research, and under the leadership of Drs. Mar...

May 25, 2021
Data and Technology
The Pan-Canadian Proteomics Centre: An Integrated Platform for Compreh...

The Proteomics Centre (PC) is a multi-node platform that combines the research and service strengths of two outstanding proteomics facilities: the University of Victoria (UVic)-Gen...

May 25, 2021
sector_ico_Health_trans Human Health
Development for a new antibiotic for methicillin resistant Staphylocco...

Methicillin-resistant Staphylococcus aureus (MRSA) is a pathogen commonly found in hospitals and other community settings. MRSA can cause several types of skin infections that can ...

May 25, 2021
sector_ico_Health_trans Human Health
Validation of Connexins and Pannexins as a target for Alzheimer’...

While most therapeutic approaches target the neurons to prevent their death in Alzheimer’s Disease (AD), this project focused both on neurons and astrocytes (glial cells in t...

May 25, 2021
sector_ico_Health_trans Human Health
IBD Genomic Medicine Consortium (iGenoMed)- translating genetic discov...

Inflammatory bowel disease (IBD) results from chronic inflammation in the digestive system. Canada has among the highest frequency of people with IBD in the world with over 250,000...

May 25, 2021
sector_ico_Health_trans Human Health
Optimization of ‘Ultra-Low-Input’ (ULI)-Chromatin immunopr...

Each cell of an organism carries the same genetic sequence, yet the cells from complex organisms such as plants or humans exhibit different features and gene regulation patterns. T...

May 25, 2021
sector_ico_Environment_trans Environment
DNA-Based Tool for Monitoring and Validating Stormwater Treatment Wetl...

Stormwater exiting roadways contains elevated levels of several metals, including antimony, chromium, copper, molybdenum, and zinc as well as heavy extractable petroleum hydrocarbo...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
A metagenomic survey of yeast populations in two Okanagan wineries...

Major wine regions worldwide have demonstrated that product differentiation by terroir enhances the marketability and perceived value of their wines. Okanagan wineries Okanagan Cru...

May 25, 2021
sector_ico_Forestry_trans Forestry
Economic Rationale and Implementation Mechanisms for Climate-Based See...

The goal of this project was to create tools to perform cost-benefit analyses which demonstrate the economic benefits of the long-term sustained funding required to create an adequ...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Application of DNA microarray technologies to clinical testing in here...

Hereditary cancers are thought to account for between 5 and 20% of cancers.  Large duplications and deletions are not uncommon in hereditary cancer syndromes, accounting for 2...

May 25, 2021
sector_ico_Health_trans Human Health
The Implementation of Pharmacogenomics into Primary Care in British Co...

Every year in Canada, severe adverse drug events cost $13.7 to 17.7 billion and claim 10-22K lives. This joint project between UBC Department of Family Practice and Telus Health ai...

May 25, 2021
sector_ico_Environment_trans Environment
Microbial community structure and function in hydraulic fracturing flu...

British Columbia’s natural gas strategy centers on development of a liquefied natural gas (LNG) sector fuelled by shale gas and the province estimates that LNG exports will g...

May 25, 2021
sector_ico_Health_trans Human Health
Genomics for Precision Drug Therapy in the Community Pharmacy...

Testing a person’s genome can predict how they will respond to certain medications — if the medications are effective and if dosages need changing. Rapid, lower-cost, n...

May 25, 2021
sector_ico_Health_trans Human Health
Simeprevir screening assay for hepatitis C therapy...

A group of BC scientists has implemented a sophisticated screening process to ensure an effective, but expensive, Hepatitis C virus (HCV) treatment will be given to only those pati...

May 25, 2021
sector_ico_Mining_trans Mining
Development of innovative tools for the environmental assessment of me...

Casino Mining Corporation was looking for a way to recover as much of the gold and copper as possible and treat effluent that results from operations in a way that least impacts th...

May 25, 2021
sector_ico_Fisheries_trans Fisheries and Aquaculture
Genomic solutions for informing sockeye repatriation and kokanee fishe...

Freshwater fisheries are an integral part of BC’s social and economic fabric. Direct, indirect and induced impacts of sport fishing totals more than $950 million. Kokanee, a ...

May 25, 2021
sector_ico_Forestry_trans Forestry
Western redcedar multi-trait genomic selection...

Western red cedar is an important export contributing to Canada’s economy. This project developed genomic resources that will facilitate the application of Genomic Selection ...

May 25, 2021
sector_ico_Forestry_trans Forestry
Implementation of genomics selection in coastal Douglas-fir breeding p...

BC's forests cover two-thirds of our total landmass and our forests generate more than $11.6 billion in economic activity each year. The main objective of this project was to asses...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
A Smart Drilling Tool for Distal Locking of Intramedullary Nails...

This project aimed to develop a 'smart' drilling tool ("SmartDrill") that can substantially reduce operating room time and virtually eliminate radiation exposure to the surgeon dur...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
A microfluidic nanoparticle formulator for systemically deliverable ge...

Short interfering RNA-lipid nanoparticles (siRNA-LNP) are a powerful research tool for in vivo functional genomics. siRNA has the potential to silence any gene by binding to and me...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Microfluidics Technologies to Separate Cells based on Rigidity...

Genome sequencing of any biological sample invariably involves a homogeneous mixture of cells and cell types, but by studying single cells, the confusion that accompanies these mix...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Rapid and Cost Effective Mutation Validation by Microfluidic Sequence ...

Genome sequencing of any biological sample invariably involves a homogeneous mixture of cells and cell types, but by studying single cells, the confusion that accompanies these mix...

May 25, 2021
sector_ico_Health_trans Human Health
Comparison of the efficacy of anti-PCSK9 biologics in the treatment of...

Treatment of sepsis includes early intravenous antibiotics and supportive resuscitation but there are currently no approved, effective drugs to treat sepsis. Cyon Therapeutics hope...

May 25, 2021
sector_ico_Health_trans Human Health
National Access Project For Cancer Testing...

Contextual Genomics has launched a National Access Project for Cancer Testing.  Currently, tumor testing is delivered by a disparate collage of academic laboratories.  Th...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Genetic Improvement of a Novel Yeast to Produce Commercially Important...

A team of BC scientists, led by UBC's Dr. Hennie van Vuuren, and investors have founded Creatus Biosciences Inc. (Creatus) to realize applications of a novel micro-organism that pr...

May 25, 2021
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