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  • YEAR
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sector_ico_Environment_trans Environment
Climate change mitigation through algal bioproduction...

Microscopic algae hold tremendous potential for addressing societal challenges in a sustainable way. One such challenge is the environmental damage caused by abandoned mines. Water...

May 25, 2021
sector_ico_Health_trans Human Health
The vaginal microbiome project team. Characterizing the role of the va...

Advances in genome sequencing and bioinformatics have provided new tools to systematically investigate the human microbiome, and the opportunity to decipher the role that microbes ...

May 25, 2021
sector_ico_Energy_trans Energy
Genetic Engineering for Photosynthetic Proteins for Solar Energy...

Solar power is an abundant sustainable energy source: in a single hour, the sun irradiates enough energy to meet humanity's needs for an entire year. However, solar energy is curre...

May 25, 2021
Data and Technology
The Metabolomics Innovation Centre...

Metabolomics is a relatively new area of science that measures the thousands of small molecules in cells, tissues and organisms. While small, these molecules, also called metabolit...

May 25, 2021
Data and Technology
The Proteomics Centre (PC): An Integrated GIN Node for Comprehensive, ...

Proteomics is the study of proteins and their interactions. Studying what proteins are expressed and in what quantities is highly complex, but can provide sophisticated information...

May 25, 2021
Data and Technology
Methods and Technology Development at the Sequencing Platform at the B...

The sequencing platform at Canada’s Michael Smith Genome Sciences Centre (GSC) at the BC Cancer Agency has been delivering large-scale DNA sequencing data efficiently and rel...

May 25, 2021
sector_ico_Health_trans Human Health
Accelerating the development of a novel outer membrane protein based v...

Chlamydia trachomatis is the causative agent of one of the most widespread bacterial sexually transmitted diseases in the world causing an estimated 92 million infections per years...

May 25, 2021
Data and Technology
BC Cancer Agency Genome Sciences Centre Genomics Technology Platform...

The sequencing analysis platform at Canada's Michael Smith Genome Sciences Centre (GSC) is at the forefront of international genomics research, and under the leadership of Drs. Mar...

May 25, 2021
Data and Technology
The Pan-Canadian Proteomics Centre: An Integrated Platform for Compreh...

The Proteomics Centre (PC) is a multi-node platform that combines the research and service strengths of two outstanding proteomics facilities: the University of Victoria (UVic)-Gen...

May 25, 2021
sector_ico_Health_trans Human Health
Development for a new antibiotic for methicillin resistant Staphylocco...

Methicillin-resistant Staphylococcus aureus (MRSA) is a pathogen commonly found in hospitals and other community settings. MRSA can cause several types of skin infections that can ...

May 25, 2021
sector_ico_Health_trans Human Health
Validation of Connexins and Pannexins as a target for Alzheimer’...

While most therapeutic approaches target the neurons to prevent their death in Alzheimer’s Disease (AD), this project focused both on neurons and astrocytes (glial cells in t...

May 25, 2021
sector_ico_Health_trans Human Health
IBD Genomic Medicine Consortium (iGenoMed)- translating genetic discov...

Inflammatory bowel disease (IBD) results from chronic inflammation in the digestive system. Canada has among the highest frequency of people with IBD in the world with over 250,000...

May 25, 2021
sector_ico_Health_trans Human Health
Optimization of ‘Ultra-Low-Input’ (ULI)-Chromatin immunopr...

Each cell of an organism carries the same genetic sequence, yet the cells from complex organisms such as plants or humans exhibit different features and gene regulation patterns. T...

May 25, 2021
sector_ico_Environment_trans Environment
DNA-Based Tool for Monitoring and Validating Stormwater Treatment Wetl...

Stormwater exiting roadways contains elevated levels of several metals, including antimony, chromium, copper, molybdenum, and zinc as well as heavy extractable petroleum hydrocarbo...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
A metagenomic survey of yeast populations in two Okanagan wineries...

Major wine regions worldwide have demonstrated that product differentiation by terroir enhances the marketability and perceived value of their wines. Okanagan wineries Okanagan Cru...

May 25, 2021
sector_ico_Forestry_trans Forestry
Economic Rationale and Implementation Mechanisms for Climate-Based See...

The goal of this project was to create tools to perform cost-benefit analyses which demonstrate the economic benefits of the long-term sustained funding required to create an adequ...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Application of DNA microarray technologies to clinical testing in here...

Hereditary cancers are thought to account for between 5 and 20% of cancers.  Large duplications and deletions are not uncommon in hereditary cancer syndromes, accounting for 2...

May 25, 2021
sector_ico_Health_trans Human Health
The Implementation of Pharmacogenomics into Primary Care in British Co...

Every year in Canada, severe adverse drug events cost $13.7 to 17.7 billion and claim 10-22K lives. This joint project between UBC Department of Family Practice and Telus Health ai...

May 25, 2021
sector_ico_Environment_trans Environment
Microbial community structure and function in hydraulic fracturing flu...

British Columbia’s natural gas strategy centers on development of a liquefied natural gas (LNG) sector fuelled by shale gas and the province estimates that LNG exports will g...

May 25, 2021
sector_ico_Health_trans Human Health
Genomics for Precision Drug Therapy in the Community Pharmacy...

Testing a person’s genome can predict how they will respond to certain medications — if the medications are effective and if dosages need changing. Rapid, lower-cost, n...

May 25, 2021
sector_ico_Health_trans Human Health
Simeprevir screening assay for hepatitis C therapy...

A group of BC scientists has implemented a sophisticated screening process to ensure an effective, but expensive, Hepatitis C virus (HCV) treatment will be given to only those pati...

May 25, 2021
sector_ico_Mining_trans Mining
Development of innovative tools for the environmental assessment of me...

Casino Mining Corporation was looking for a way to recover as much of the gold and copper as possible and treat effluent that results from operations in a way that least impacts th...

May 25, 2021
sector_ico_Fisheries_trans Fisheries and Aquaculture
Genomic solutions for informing sockeye repatriation and kokanee fishe...

Freshwater fisheries are an integral part of BC’s social and economic fabric. Direct, indirect and induced impacts of sport fishing totals more than $950 million. Kokanee, a ...

May 25, 2021
sector_ico_Forestry_trans Forestry
Western redcedar multi-trait genomic selection...

Western red cedar is an important export contributing to Canada’s economy. This project developed genomic resources that will facilitate the application of Genomic Selection ...

May 25, 2021
sector_ico_Forestry_trans Forestry
Implementation of genomics selection in coastal Douglas-fir breeding p...

BC's forests cover two-thirds of our total landmass and our forests generate more than $11.6 billion in economic activity each year. The main objective of this project was to asses...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
A Smart Drilling Tool for Distal Locking of Intramedullary Nails...

This project aimed to develop a 'smart' drilling tool ("SmartDrill") that can substantially reduce operating room time and virtually eliminate radiation exposure to the surgeon dur...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
A microfluidic nanoparticle formulator for systemically deliverable ge...

Short interfering RNA-lipid nanoparticles (siRNA-LNP) are a powerful research tool for in vivo functional genomics. siRNA has the potential to silence any gene by binding to and me...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Microfluidics Technologies to Separate Cells based on Rigidity...

Genome sequencing of any biological sample invariably involves a homogeneous mixture of cells and cell types, but by studying single cells, the confusion that accompanies these mix...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Rapid and Cost Effective Mutation Validation by Microfluidic Sequence ...

Genome sequencing of any biological sample invariably involves a homogeneous mixture of cells and cell types, but by studying single cells, the confusion that accompanies these mix...

May 25, 2021
sector_ico_Health_trans Human Health
Comparison of the efficacy of anti-PCSK9 biologics in the treatment of...

Treatment of sepsis includes early intravenous antibiotics and supportive resuscitation but there are currently no approved, effective drugs to treat sepsis. Cyon Therapeutics hope...

May 25, 2021
sector_ico_Health_trans Human Health
National Access Project For Cancer Testing...

Contextual Genomics has launched a National Access Project for Cancer Testing.  Currently, tumor testing is delivered by a disparate collage of academic laboratories.  Th...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Genetic Improvement of a Novel Yeast to Produce Commercially Important...

A team of BC scientists, led by UBC's Dr. Hennie van Vuuren, and investors have founded Creatus Biosciences Inc. (Creatus) to realize applications of a novel micro-organism that pr...

May 25, 2021
sector_ico_Health_trans Human Health
Defining the Mouse Cytome...

The International Mouse Phenotyping Consortium (IMPC) is a $500 million world-wide partnership of research institutions focused on understanding the function of every gene in the m...

May 25, 2021
sector_ico_Health_trans Human Health
Development of a non-invasive, digital PCR-based molecular test for ri...

Oral cancer (OC) is a global health problem with high incidence and high mortality. OC has worldwide impact, accounting for 274,000 new cases and 145,000 deaths each year. The 5 ye...

May 25, 2021
sector_ico_Health_trans Human Health
BC Wild Mushrooms – Developing a Library of Chemical Fractions f...

Mushrooms have been used as a source of traditional medicine for thousands of years by different cultures around the world. However, it is estimated that only 10% of mushroom speci...

May 25, 2021
sector_ico_Environment_trans Environment
Deep Sequencing of Marine Biodiversity: Speciation Genes in Sea Stars...

This project extends a previous Genome BC SOF aimed to identify speciation genes in an iconic BC sea star. The  focus of this work was on analyzing speciation genes that cause...

May 25, 2021
Data and Technology
Advanced Assembly Assessment and Annotation...

This project built on past expertise to remedy a strategic gap in the availability of actively supported, scalable bioinformatics tools for genome assembly. The first objective was...

May 25, 2021
sector_ico_Health_trans Human Health
Modeling Human Lymphoma Mutations in Mice...

Next-generation sequencing has made it feasible to sequence cancer genomes to determine the underlying genetic causes of the disease. The objective of this project was to establis...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Molecular and physiological characterization of early ripening events ...

Grapevine is one of the most widely cultivated fruit crops. Despite its importance in determining fruit and wine economic value, the regulation of fruit ripening at a molecular lev...

May 25, 2021
sector_ico_Health_trans Human Health
Metagenomic analysis of lung infiltrates in patients with leukemia...

Patients with neutropenia (an abnormally low level of neutrophils) are at a high risk for life-threatening bacterial and/or fungal infections after high-dose chemotherapy for acute...

May 25, 2021
Data and Technology sector_ico_Environment_trans Environment
Single Virus Genomics: Adoption and Optimization of Single Cell Techno...

Viruses are by far the most abundant "lifeforms" in the oceans and are the reservoir of most of the genetic diversity in the sea. Every second, approximately 1023 viral infections ...

May 25, 2021
sector_ico_Health_trans Human Health
Harnessing cladoniamide biosynthesis for colon cancer therapy...

Cladoniamides represent an important new class of anticancer drugs with nanomolar inhibition of tumor cell line growth. However, they are difficult to synthesize as a natural produ...

May 25, 2021
sector_ico_Health_trans Human Health
Development of an actionable molecular test for risk assessment of ora...

Oral cancer is a global health problem with high incidence and poor mortality, and the presence and degree of dysplasia remain the gold standard for cancer progression. Approximate...

May 25, 2021
sector_ico_Health_trans Human Health
Synergizing -omics to discover treatable intellectual disabilities...

Intellectual disability (ID) is a lifelong, debilitating condition affecting 2.5% of children and adults worldwide. Most IDs are of genetic origin, but causal variants are identifi...

May 25, 2021
sector_ico_Health_trans Human Health
Bioinformatic Identification of Optimal Targets and Therapeutic Antibo...

This project aimed to develop a computational approach to identify potential therapeutic opportunities by examining protein coding changes across a large number of tumours sequence...

May 25, 2021
sector_ico_Environment_trans Environment
Simplifying Complex Genome Generation...

Ranidae/Bullfrogs are the "true frogs" that have the widest global distribution. As the largest amphibian family, bullfrogs have an undeniable role as sentinel species, food source...

May 25, 2021
sector_ico_Health_trans Human Health
Using Science, Technology, and Society Studies Research to Move Genomi...

Using BC’s genomics research and business sector as the site for applied research, this project aimed to address data integration issues faced when integrating data from mult...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Detecting and Characterizing Chimeric Transcripts in Mouse Tissues...

Chimeric transcriptions are newly discovered genetic events that do not correlate with the current model for gene expression and have potential impacts and application in cancer di...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Vaccinomics for animal disease...

Infectious diseases continue to be a leading cause of morbidity and mortality in domestic animals and are of significant concern to human health due to the potential for the transf...

May 25, 2021
sector_ico_Health_trans Human Health
Antisense PET Imaging of mRNA Expression Using F-18 Labeled CPP-PNA an...

Molecular imaging (MI) is a powerful tool that probes the function of living systems, enabling non-invasive determination of physiological changes that occur during the onset and p...

May 25, 2021
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