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  • YEAR
    • 2017
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sector_ico_Environment_trans Environment
Genomic studies of explosives biodegradation...

Many explosives used by militaries and other industries around the world use nitramine chemicals as the source of the high energy needed during explosions. RDX is a commonly used e...

May 25, 2021
sector_ico_Fisheries_trans Fisheries and Aquaculture
Genomics in Lice and Salmon (GiLS)...

The health of both wild and farmed salmon can be severely impacted by sea lice that live on the skin of the salmonid fish. Lice infections can cause production costs of Canadian fa...

May 25, 2021
Data and Technology
BCCA-GSC Technology Development Platform...

This platform intends to seek out biomedical and life science technology opportunities that have commercial potential by building on existing relationships with clinicians and scie...

May 25, 2021
Data and Technology
The University of Victoria – Genome BC Proteomics Centre...

Funding enabled the facility to acquire new and high-end equipment such as Mass Spectrometry to make this the best equipped proteomics facility in Canada and one of the best-equipp...

May 25, 2021
Data and Technology
The Genome Sciences Centre...

Sequencing and Mapping is the largest platform technology to be supported by Genome BC. It has been created through a partnership between Genome BC and the Genome Sciences Centre (...

May 25, 2021
Data and Technology
ST&IC Laboratory For Advanced Genome Analysis...

The Laboratory for Advanced Genome Analysis (LAGA) is a multiplatform innovation centre, at the Vancouver Prostate Centre (VPC), that integrates academic research and service provi...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Towards Single Cell Genomics...

Genome sequencing of any biological sample invariably involves a homogeneous mixture of cells and cell types, but by studying single cells, the confusion that accompanies these mix...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
High Throughput High-Dimensional Multi-parametric Analysis of the Immu...

The bioinformatics tools for flow cytometry (FCM) were many years behind comparing to other platforms in genomics and proteomics. The objective of this project was to create new to...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Production-scale Deployment of Next-generation Sequencing Instruments...

Recent developments in DNA sequencing technologies have changed the way scientists collect and interpret genomic data as these “next-generation sequencers” can generate...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
MS-based Structural Proteomics for Drug Development and Design...

Aside from the overall time it usually takes to develop a drug before it can be introduced into the market - usually > 10 years - two major challenges to developing a new drug a...

May 25, 2021
sector_ico_Health_trans Human Health
CanEuCre – Genomic Resources Advancing Therapies for Brain Disor...

The mouse is the premier model organism for human genetic and genomic medical research. Large scale efforts in mouse-functional genomics are currently ongoing in the US, Canada, an...

May 25, 2021
sector_ico_Forestry_trans Forestry
The Mountain Pine Beetle Epidemic – Using genomics of the intera...

This project (Tria I) on mountain pine beetle was looking at the mechanisms for managing the beetles, identifying and breeding resistant trees, and understanding the biology of the...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
WineGen – Genomics of Viticulture and Enology...

This applied research project builds on the previous GrapeGen project to further advance new knowledge about grape biology (viticulture) and wine yeasts to improve winemaking proce...

May 25, 2021
sector_ico_Health_trans Human Health
IND Enabling Studies for Antisense Oligonucleotides Targeting Key Regu...

Iron is essential to bind oxygen and transport electrons for all living organisms, but iron overload and maldistribution have been implicated in the etiology of many disorders, inc...

May 25, 2021
sector_ico_Health_trans Human Health
Genotype-Specific Approaches to Therapy in Childhood- The Canadian Pha...

Adverse reactions to approved prescription drugs are a major health concern and children are particularly vulnerable. These adverse drug reactions (ADRs) cause 10,000-22,000 deaths...

May 25, 2021
Data and Technology
UVic – Genome BC Proteomics Centre...

Funding enabled the facility to acquire new and high-end equipment such as Mass Spectrometry to make this the best equipped proteomics facility in Canada and one of the best-equipp...

May 25, 2021
sector_ico_Fisheries_trans Fisheries and Aquaculture
Consortium for Genomic Research on All Salmonids Project (cGRASP)...

Salmon, trout and char comprise the salmonids, a group of fish that are of great economic and societal importance to Canada, particularly in the coastal, rural, and Aboriginal comm...

May 25, 2021
sector_ico_Health_trans Human Health
Pleiades Promoter Project...

Gene therapy delivers healthy genes to replace dysfunctional ones and has been tried worldwide with some tantalizing successes as well as disappointing failures in some human trial...

May 25, 2021
sector_ico_Health_trans Human Health
Pathogenomics of Innate Immunity (PI2)...

Despite being exposed to tens of thousands of potentially pathogenic microbes daily, we rarely succumb to infection, primarily due to our innate immune system. This ‘innate-i...

May 25, 2021
sector_ico_Health_trans Human Health
Dissecting Gene Expression Networks in Mammalian Organogenesis...

The mouse has been established as an important model organism in biomedical studies due to the high degree of genetic homology between mouse and humans plus the powerful ability to...

May 25, 2021
sector_ico_Health_trans Human Health
High Resolution Analysis of Follicular Lymphoma Genomes...

Follicular lymphoma (FL), the most common type of lymphoma, is a cancer of the cells of the immune system. Follicular lymphoma is associated with a specific genome rearrangement wh...

May 25, 2021
sector_ico_Fisheries_trans Fisheries and Aquaculture
Building a GE3LS Architecture (GE3LS ARC)...

An objective of Genome Canada is to ‘ensure leadership in ethical, environmental, economic, legal and social issues (GE³LS) related to genomics and proteomics research.&...

May 25, 2021
sector_ico_Forestry_trans Forestry
Conifer Forest Health Genomics...

Spruce is the dominant conifer species in Canada and is the most important tree of the Canadian forest industry. This project aimed to identify the genetic traits of spruce trees t...

May 25, 2021
sector_ico_Health_trans Human Health
Functional Genomics for Emerging Infectious Diseases (PREPARE) Project...

As a global community, we are constantly fighting infectious diseases that threaten health and reduce productivity. Emerging infectious diseases (EIDs) include drug resistant staph...

May 25, 2021
sector_ico_Health_trans Human Health
Efficient Identification and Cloning of Single Gene Deletions in the N...

The nematode C. elegans is a powerful research tool to investigate fundamental questions about biology. It was the first multicellular organism for which a complete DNA sequence wa...

May 25, 2021
sector_ico_Health_trans Human Health
Better Biomarkers of Acute and Chronic Allograft Rejection...

After transplantation of a heart, kidney, or liver, the immune system may attack the foreign organ so patients are treated with immunosuppressant medication to prevent rejection. H...

May 25, 2021
sector_ico_Health_trans Human Health
Genomic Tools for Diagnosis and Evaluation of Mental Retardation...

Mental retardation, which is usually defined as an IQ score below 70, occurs in approximately 1% of the population. It is the most frequent cause of severe life-long disability in ...

May 25, 2021
sector_ico_Health_trans Human Health
Application of Pharmacogenomics for Rational Chemotherapy of Lung Canc...

This lung cancer project has been instrumental in determining genetic markers that could inform clinicians of the potential success (or failure) of a particular treatment before ch...

May 25, 2021
sector_ico_Health_trans Human Health
Innovative Genomic Applications to Develop Clinical Biomarkers and Nov...

Iron is essential to bind oxygen and transport electrons for all living organisms, but iron overload and maldistribution have been implicated in the etiology of many disorders, inc...

May 25, 2021
sector_ico_Health_trans Human Health
Development and Validation of Comparative Genomic Hybridization Arrays...

Cancer research involves examining genetic changes associated with cancer development and progression. This project has developed and evaluated tiling resolution whole genome array...

May 25, 2021
sector_ico_Health_trans Human Health
Genotype Specific Approaches to Therapy in Childhood (GATC)...

Adverse reactions to approved prescription drugs are a major health concern and children are particularly vulnerable. These adverse drug reactions (ADRs) cause 10,000-22,000 deaths...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Bovine Genome Sequencing Program- Full-length cDNA Sequencing...

The bovine genome is similar in size to the genomes of humans, with approximately 3 billion base pairs and approximately 25,000 genes. Sequences for full-length cDNA clones derived...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
GrapeGen- A Genomic Approach to the Identification of the Genetic and ...

This research project investigated the grape ripening process at a molecular level and the changes in that process in response to various environmental conditions. Grapevine (Vitis...

May 25, 2021
sector_ico_Health_trans Human Health
Functional Pathogenomics of Mucosal Immunity...

Despite being exposed to tens of thousands of potentially pathogenic microbes daily, we rarely succumb to infection, primarily due to our innate immune system. This ‘innate-i...

May 25, 2021
sector_ico_Health_trans Human Health
Expression Profiles of Cells and Tissues in C. elegans...

The nematode C. elegans is a powerful research tool to investigate fundamental questions about biology. It was the first multicellular organism for which a complete DNA sequence wa...

May 25, 2021
Data and Technology
Sequencing & Mapping...

Sequencing and Mapping is the largest platform technology to be supported by Genome BC. It has been created through a partnership between Genome BC and the Genome Sciences Centre (...

May 25, 2021
sector_ico_Forestry_trans Forestry
Treenomix- Mechanisms of Wood Formation and Pest Resistance in Forest ...

Sustainable forestry in Canada will benefit from a genomic understanding of trees. The researchers looked at the spruce and poplar species, plus an applicable and biologically well...

May 25, 2021
sector_ico_Health_trans Human Health
Brain Channelopathies – Target Validation and Novel Therapeutic ...

This project expected to provide new insights into how particular genetic alterations affect calcium channel properties resulting in the disruption of normal brain functions, and c...

May 25, 2021
sector_ico_Health_trans Human Health
Somatostatin 2 Receptor (SSTR2) Antagonists for the Prevention of Hypo...

The primary limitation to effective insulin therapy to improve blood sugar control in Type 1 diabetes (T1D) is the risk of hypoglycemia, also known as low blood sugar. Hypoglycemia...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Centre for Epigenome Mapping Technologies (CEMT) Phase 2...

The term epigenome refers to chemical modifications of DNA and proteins that control the structure and regulation of the "genome," referring to all the DNA within our cel...

May 25, 2021
sector_ico_Health_trans Human Health
Discovery and development of novel anti-bacterial drugs...

The primary objective of this project is to confirm the antibacterial activity of compound 043 and 049 analogs in the presence and absence of a synergistic antibiotic and esta...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Development and commercialization of standardized reagents and guideli...

Aside from the overall time it usually takes to develop a drug before it can be introduced into the market - usually > 10 years - two major challenges to developing a new drug a...

May 25, 2021
sector_ico_Health_trans Human Health
Synthetic Lethality – Targeting FEN1 for more selective cancer t...

This project proposes to screen additional CDRD chemical libraries in order to identify a greater number of unique compounds that inhibit FEN1 at low micromolar potency. In paralle...

May 25, 2021
sector_ico_Health_trans Human Health
Canadian Humans and the Microbiome Program...

As many as 1,000 different species of bacteria make their homes inside or on humans. Yet, we have had little understanding of their role in human health and disease. New scientific...

May 25, 2021
Data and Technology
Microarray Platform...

Microarray technology provides a fast and economical method for expression analysis of tens of thousands of genes concurrently. The differences in gene expression between discreet ...

May 25, 2021
Data and Technology
Microarray Facility...

Microarray technology provides a fast and economical method for expression analysis of tens of thousands of genes concurrently. The differences in gene expression between discreet ...

May 25, 2021
Data and Technology
Genomics Technology Platform...

The bioinformatics platform at Canada's Michael Smith Genome Sciences Centre (GSC) is at the forefront of genomics research and collaboration. It has made seminal contributions to ...

May 25, 2021
sector_ico_Health_trans Human Health
Inhibitors of New Delhi Metallo-B-Lactamase 1...

Antibiotic resistance in pathogenic microoganisms is now regarded to be a major threat to human health. One of the most worrying examples of this problem is the rapid emergence and...

May 25, 2021
sector_ico_Health_trans Human Health
Inhibitors of the CBX7-H3K27me3 epigenetic interaction for castration ...

Prostate cancer is the most commonly diagnosed non-skin cancer in Canadian men, with an estimated 26,500 new cases in 2012. Current treatment options for castration-resistant prost...

May 25, 2021
sector_ico_Health_trans Human Health
High-throughput Screening in C. elegans for Anthelmintics to treat Fil...

Onchocerciasis (river blindness) and lymphatic filiariasis (elephantiasis) are the most serious human health problems caused by parasitic worms. At least 25 million people are infe...

May 25, 2021
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