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  • YEAR
    • 2017
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sector_ico_Agrifood_trans Agrifood
Temperature-sensitive Salmonella veterinary vaccines...

This proof of concept project aimed at developing a new type of vaccine to be used in the poultry industry to immunize against Salmonella enterica. This bacterium is one of the mos...

May 25, 2021
sector_ico_Health_trans Human Health
Development of expression signatures to improve diagnosis and prognosi...

Muscle-invasive bladder cancer is an aggressive disease that leads to death in approximately half of patients despite optimal multimodal therapy. The mainstay of treatment in bladd...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Signal Detection Development for Sequence Specific SCODA...

Building on previously funded research, this project aimed to develop a rapid, point of care DNA and RNA sequence detection instrument for diagnosis of infections. This collaborati...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Application of next-generation sequencing technologies to clinical tes...

Recent developments in DNA sequencing technologies have changed the way scientists collect and interpret genomic data as these “next-generation sequencers” can generate...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Sequencing and comparative genome mapping of Chardonnay grapevine clon...

Chardonnay is the second most abundant white wine grape variety in the world and is the second most planted white variety in British Columbia. Chardonnay clones exhibit remarkable ...

May 25, 2021
sector_ico_Forestry_trans Forestry
Genomics Research Entrepreneurship to Accelerate Translation (GREAT)...

The GREAT project leveraged the joint strengths of The University of British Columbia's (UBC) University-Industry Liaison Office (UILO) and Sauder School of Business and assembled ...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Genomic Analysis of Wetland Sediment as a Tool for Avian Influenza Vir...

In 2014/2015 an outbreak of highly pathogenic Avian Influenza (AI) struck British Columbia. A total of 13 poultry farms were affected and approximately 240,000 birds died or were d...

May 25, 2021
sector_ico_Mining_trans Mining
Metagenomics to assess impacts of the Mount Polley Mine tailings dam b...

The Mount Polley Mine tailings dam breached on August 4, 2014. Over the following 2-3 days approximately 24 million m3 of mine-influenced, non-treated water and mine tailings sedim...

May 25, 2021
sector_ico_Health_trans Human Health
Impact of the microbiota on immune development and disease...

There is increasing evidence that the intestinal microbiota impact immune development and disease. Recent evidence suggests that shifts in resident microbiota (normal flora) may pl...

May 25, 2021
sector_ico_Fisheries_trans Fisheries and Aquaculture
Inventory and Assessment of Health Risk of Microbes in BC (Phase 2a)...

Over 90% of juvenile salmon migrating from freshwater into the ocean will die before returning to freshwater to spawn, and disease may be a significant factor contributing to this ...

May 25, 2021
sector_ico_Fisheries_trans Fisheries and Aquaculture
Enhancing Production in Coho: Culture, Community, Catch (EPIC4)...

With 25% of the world's coastline and 16% of the world's freshwater, Canada is well-positioned to build a stronger and vibrant blue economy in an ecologicall...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Reverse Vaccinology Approach for the Prevention of Mycobacterial Disea...

Infectious diseases continue to be a leading cause of sickness and death in livestock and are of concern to human health due to their potential to be transferred to people. Vaccina...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Genomics of Abiotic Stress Resistance in Wild and Cultivated Sunflower...

Drought, flooding, salt and low nutrient levels negatively affect plant growth and lower crop productivity. These environmental stresses have the greatest impact on our highly adap...

May 25, 2021
Data and Technology
The Proteomics Centre (PC)...

Proteomics is "the protein complement to the genome"- the study of proteins and their interactions. Genes express proteins; these proteins, in turn, do most of the work in cells. S...

May 25, 2021
Data and Technology
Sequencing Platform at the BC Cancer Agency Genome Sciences Centre...

The GSC performs primarily whole genome, transcriptome, and targeted amplicon sequencing and provides additional services in epigenomics, immunogenomics and metagenomics. The Centr...

May 25, 2021
Data and Technology
Genome BC Genomics Innovation Centre at the BC Cancer Agency Genome Sc...

This Genome Canada Innovation Centre (IC) is embedded within the BC Cancer Agency Genome Sciences Centre. The IC is directed by Drs. Marco Marra, Steven Jones and Ro...

May 25, 2021
Data and Technology sector_ico_Health_trans Human Health
Development of Disease Biomarker Assessment Assays and Kits for Target...

Protein biomarker research has been limited by the lack of available tools to perform rapid and robust quantitation, especially in small sample volumes. Existing technologies ...

May 25, 2021
sector_ico_Health_trans Human Health
Measuring and modeling tumour evolution from next generation sequencin...

Breast and ovarian cancers are significant causes of disease and death among North American women. Tumours in these cancers can acquire different mutations, resulting in cells that...

May 25, 2021
sector_ico_Health_trans Human Health
A compressed sensing framework for identifying differentially expresse...

New technology provides fast and accurate ways to analyze RNAs (which act as messengers carrying instructions from DNA) that code protein in a tissue. While there are many potentia...

May 25, 2021
sector_ico_Health_trans Human Health
Tool for proteome-wide identification of regulatory switches...

Despite significant progress in diagnosis and treatment, cancer remains Canada’s leading cause of death. Although scientists have made major efforts in identifying mutations ...

May 25, 2021
sector_ico_Health_trans Human Health
Applied Bioinformatics of Cis-regulation for Disease Exploration (ABC4...

When people go to a doctor, they want to be treated for what ails them and they want to be treated in a way that is most appropriate for them. This is the ultimate goal, often call...

May 25, 2021
sector_ico_Health_trans Human Health
Computational interpretation of cancer genomes: Defining mutational la...

Tumours develop through the accumulation of mutations in DNA. Recent advances in high-throughput (next-generation) DNA sequencing allow researchers rapid identification of mutation...

May 25, 2021
sector_ico_Health_trans Human Health
A Federated Bioinformatics Platform for Public Health Microbial Genomi...

Despite advances in medical, sanitary, and public health practices, communicable diseases remain a serious threat to the health and economies of Canadians and people worldwide. Who...

May 25, 2021
sector_ico_Health_trans Human Health
Next Generation Bioinformatics for Clinical Genomics: using de novo as...

Substantial advancements in cancer care and healthcare economics can be realized through the development of genomics technologies to detect variations and mutations in DNA and RNA ...

May 25, 2021
sector_ico_Health_trans Human Health
Orphan Diseases- Identifying Genes and Novel Therapeutics to Enhance T...

One in twelve Canadians suffers from an “Orphan Disease” (OD). These are diseases that have not been adopted by the pharmaceutical industry because they affect a small ...

May 25, 2021
sector_ico_Energy_trans Energy
POPCAN- Genetic improvement of poplar trees as a Canadian bioenergy fe...

The extensive use of fossil fuels is a key contributor to climate change. The Government of Canada mandated a five percent renewable fuel content in gasoline, however production is...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Next-generation Integrated Pest Management tools for beekeeping...

Bees play a major role in agriculture as pollinators of crops. Over the past few years, North American beekeepers have lost colonies at an alarming rate. This project aimed to deve...

May 25, 2021
sector_ico_Health_trans Human Health
Stratifying and Targeting Pediatric Medulloblastoma Through Genomics...

Cancer is the leading cause of non-accidental death in Canadian children, and brain tumors (medulloblastoma) are the leading cause of pediatric cancer deaths. The aggressive treatm...

May 25, 2021
sector_ico_Environment_trans Environment
Applied Metagenomics of the Watershed Microbiome...

Canada's watersheds are important natural resources, providing drinking water as well as water for agricultural, industrial and recreational uses. Growing demands from industry and...

May 25, 2021
sector_ico_Forestry_trans Forestry
Genomics-Based Forest Health Diagnostics and Monitoring...

Canada’s forests are increasingly under threat by pests and pathogens, resulting in annual losses of about $2 billion. The Tree Aggressors Identification using Genomic Approa...

May 25, 2021
sector_ico_Forestry_trans Forestry
SMarTForest- Spruce Marker Technologies for Sustainable Forestry...

Forestry products contribute approximately $23.1 billion to Canada's GDP. The SMarTForest team developed genomic selection methods as tree breeding tools which provide accurate pre...

May 25, 2021
sector_ico_Forestry_trans Forestry
Harnessing microbial diversity for sustainable use of forest biomass r...

In order to remain competitive, the Canada’s forest industry must develop both better forest management and extract forest biomass related products that are of value to custo...

May 25, 2021
sector_ico_Forestry_trans Forestry
AdapTree- Assessing the adaptive portfolio of reforestation stocks for...

In BC and Alberta alone, ~150 million spruce and lodgepole pine trees are planted annually, however, climate change is threatening forest health by causing a mismatch between the n...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Value Addition to Genomics and GE3LS (VALGEN)...

Research in genomics progresses at a rapid pace, and drives innovation in key areas of economically important research. The VALGEN project was designed to understand and respond to...

May 25, 2021
sector_ico_Energy_trans Energy
Metagenomics for Greener Production and Extraction of Hydrocarbon Ener...

This project proposed to characterize whole genomes of bacterial communities that naturally live in environments from which we extract energy, such as oil sands and coal beds. ...

May 25, 2021
sector_ico_Energy_trans Energy
Synthetic Biosystems for the Production of High-Value Plant Metabolite...

The PhytoMetaSyn Project used massively parallel DNA sequencing to investigate the processes and biosynthetic pathways by which selected plant species produced high-value plant met...

May 25, 2021
sector_ico_Energy_trans Energy
Genomics of Sunflower...

Worldwide, sunflower oilseed crops are valued at about $20 billion annually and sunflower species are grown commercially on 22 million hectares around the globe, currently the worl...

May 25, 2021
sector_ico_Forestry_trans Forestry
Genomics-Enhanced Forecasting Tools to Secure Canada’s Near-Term...

The mountain pine beetle outbreak has caused unprecedented damage to the Canadian forest industry. The current infestation has affected more than 18 million hectares of pine forest...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Grape and Wine Genomics...

The contribution of BC wine sales to provincial agri-business has grown significantly over the past decade. In 2011, the BC wine and grape industry contributed a total of $2.01Bill...

May 25, 2021
sector_ico_Health_trans Human Health
Finding of Rare Disease Genes in Canada (FORGE Canada)...

Rare genetic diseases in children have an enormous impact on the well-being of Canadian families, causing birth defects, intellectual disability, abnormal growth, or organ failure....

May 25, 2021
sector_ico_Health_trans Human Health
The Canadian Pediatric Cancer Genome Consortium- Translating next-gene...

Cancer is the most common cause of non-accidental death in children from infancy to young adulthood. In Canada, ~1,400 children (0-18 years of age) will be diagnosed with cancer ev...

May 25, 2021
sector_ico_Health_trans Human Health
Implementation of a Pharmacogenetic ADR Prevention Program in BC...

Adverse reactions to approved prescription drugs are a major health concern and children are particularly vulnerable. These adverse drug reactions (ADRs) cause 10,000-22,000 deaths...

May 25, 2021
sector_ico_Health_trans Human Health
Genomics applied to the management of high-risk AML/myelodysplastic sy...

AML affects approximately 200 British Columbians per year, and is fatal without appropriate therapy. Treatment options include chemotherapy and stem cell transplantation. Although ...

May 25, 2021
Data and Technology
UVic – Genome BC Proteomics Centre...

Funding enabled the facility to acquire new and high-end equipment such as Mass Spectrometry to make this the best equipped proteomics facility in Canada and one of the best-equipp...

May 25, 2021
Data and Technology
Genomics Innovation Centre at the BC Cancer Agency Genome Sciences Cen...

Sequencing and Mapping is the largest platform technology to be supported by Genome BC. It has been created through a partnership between Genome BC and the Genome Sciences Centre (...

May 25, 2021
sector_ico_Mining_trans Mining
The Development of Genomic Tools for Monitoring and Improving Passive ...

Mine drainage and other waste waters are potential sources of contamination for many different aquatic environments. Current waste water treatment methods require large scale chemi...

May 25, 2021
sector_ico_Agrifood_trans Agrifood
Apis mellifera Proteomics of Innate reSistance (APIS)...

The APIS project focused on the identifications of biomarkers of disease resistance in honey bees. Although treatments are available, increased drug resistance and the concern of c...

May 25, 2021
sector_ico_Fisheries_trans Fisheries and Aquaculture
Genomic Tools for Fisheries Management (FishMan Omics)...

The long-term viability of the wild salmon industry, worth hundreds of millions of dollars in BC, has been threatened recently by extreme variability in annual returns and declines...

May 25, 2021
sector_ico_Environment_trans Environment
Genomic approaches to microbial community monitoring as a forest manag...

The health of the microbial ecosystem of forest soil is crucial to sustainable forest management. The complex and vital interactions that occur between species of microorganisms in...

May 25, 2021
sector_ico_Energy_trans Energy
Optimized Populus feedstocks and novel enzyme systems for a British Co...

The goal of this project was to use genomic and metabolomic approaches to characterize the phenotypic and genetic diversity in of native BC Populus trichocarpa (black cottonwood, o...

May 25, 2021
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