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sector_ico_Health_trans Human Health

Using Methods of Chemical Genomics for Developing Potent Androgen Receptor Inhibitors with a Novel Mode of Action

  • Project Leaders: Artem Cherkasov, Paul Rennie
  • Institutions: University of British Columbia (UBC)
  • Budget: $324000
  • Program/Competition: Strategic Opportunities Fund
  • Genome Centre(s): Genome British Columbia
  • Status: Closed

These research projects aim to address current issues in the treatment of advanced, recurrent or metastatic prostate cancer. By using advanced methods in computational chemogenomics, medicinal chemistry and biological screening the team aims to advance an entirely new class of drugs that has recently been developed at the Vancouver Prostate Centre. Genome BC funding helped with the development of a lead compound that may lead to improved drugs instrumental in enhancing effectiveness of treatment.