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Proteomics is “the protein complement to the genome”- the study of proteins and their interactions. Genes express proteins; these proteins, in turn, do most of the work in cells. Studying what proteins are expressed and in what quantities is highly complex, but can provide sophisticated information about an organism’s condition. A relatively new field (less than 20 years old), proteomics has evolved rapidly due, in large part, to improvements in mass spectrometry instrumentation and methods that have allowed researchers to probe the proteome with unprecedented depth, breadth and detail.
The Proteomics Centre (PC) is a central hub for proteomics research in Canada. It combines the cutting-edge research and strengths of the University of Victoria-Genome BC Proteomics Centre and the University of British Columbia Proteomics Core Facility to provide clients with a “one-stop shop” for an expansive range of high-quality proteomics services.
Funded through the Platforms and STICs programs with current funding from the Genomics Innovation Network program, the PC has become a world leader in mass-spectrometry-based proteomics. The PC has developed innovative proteomics-based technologies, enhanced the quality and range of services offered, and remained cutting-edge in the field of proteomics research. Over 60 publications, over 200 presentations, 2 spin-off companies, 1 patent, and numerous collaborations resulted from the initial funding to the PC.
With the current GIN funding, the PC will continue to provide high quality proteomics services by 1) developing novel technologies that push the boundaries of sensitivity, specificity, robustness, coverage, precision, depth, and throughput for proteomics assays; 2) optimizing, automating, and reducing the cost of services while increasing throughput; and 3) increasing the range of technologies to meet client needs.
The PC was also awarded a Technology Development fund which will allow it to continue to create and improve upon the methods and software used in mass-spectrometry-based proteomics.