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Epigenetic mechanisms for the development of asthma

C35AST
  • Project Leaders: Denise Daley
  • Institutions: University of British Columbia (UBC)
  • Budget: $1,000,000
  • Competition: Canadian Epigenetics, Environment and Health Research Consortium (CEEHRC) Network
  • Genome Centre(s): Genome BC
  • Fiscal Year: 2013
  • Status: Active

Asthma is a common chronic disorder that affects both children and adults and causes decreased quality of life for those who suffer from the illness and for their families. Asthma affects as many as 300 million people in the world and is the cause of 1 in every 250 deaths world-wide. There is a genetic predisposition to asthma but increasing evidence shows that environmental insults such as smoking exposure, pollution, viruses, and common allergens are involved in the development of asthma. This study is designed to see how these genetic and environmental factors interact to contribute to asthma. This knowledge could lead to preventative public health policies and/or new therapies.