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sector_ico_Health_trans Human Health

Development of an actionable molecular test for risk assessment of oral precancers

  • Project Leaders: Catherine Poh, Aly Karsan
  • Institutions: BC Cancer (Previously BC Cancer Agency (BCCA))
  • Budget: $199950
  • Program/Competition: Strategic Opportunities Fund
  • Genome Centre(s): Genome British Columbia
  • Fiscal Year: 2013
  • Status: Closed

Oral cancer is a global health problem with high incidence and poor mortality, and the presence and degree of dysplasia remain the gold standard for cancer progression. Approximately 250-300 new dysplasias are identified each year in BC.

The lack of an effective predictor for the progress of moderate dysplasias (oral precancers) is the main reason for the difficulties of triaging high and low-risk patients as well as the unnecessary costs incurred to the medical system and patients themselves.

This project developed a cost-effective test to triage oral precancers with the potential to streamline the workflow in the clinical setting.