Human Health
COVID-19 Sequencing and Modelling Integrated with Laboratory and Epidemiological Sources (SMILES)
VAC008- Project Leaders: Agatha Jassem
- Institutions: University of British Columbia (UBC)
- Budget: $200000
- Program/Competition: Rapid SARS-CoV-2 Vaccine Research Initiative in BC
- Genome Centre(s): Genome British Columbia
- Fiscal Year: 2021
- Status: Closed
Vaccine escape mutants have the potential to undermine the effectiveness of the global vaccination campaign against SARS-CoV-2. The team will develop a surveillance program to detect and sequence viral variants emerging from vaccine breakthrough infections. These mutants will be tested experimentally to understand their responsiveness to vaccine-induced immunity, and modeling will be incorporated to project the impacts of vaccine escape mutants on transmission and pandemic progression in BC.
