The project team based in BC Genome Sciences Centre developed a computational tool named Trans-AbySS that is highly effective in identifying novel RNA molecules. The project team developed a method that could correctly reconstruct thousands of RNA sequences from short sequence reads generated by next generation sequencing technologies. Specifically, with Trans-ABySS, the team demonstrated that it can be used assemble to reconstruct (from millions of tiny segments) the total RNAs in a sample for non-Hodgkins lymphoma. In fact, the project team was able to detect known RNA mutations associated with this disease. The project team aims to apply this approach to survey a wider range of other cancer types.