Prenatal Case Study: Possible Down Syndrome

Curriculum Link > Biology 12

Protein Synthesis

• Explain how mutations in DNA affect protein synthesis

What is the animation about?
In this interactive case study, students will follow a couple who are making a choice about testing their pregnancy. Students get to choose one of two paths as they learn about the process of genetic counselling and the hereditary links to Down Syndrome.

View the online book - Prenatal Case Study: Possible Down Syndrome

Using the animation in the classroom

• Students can follow the interactive case study independently. This could be carried out as a library, or homework activity.
• You could follow the case study as a class and then have students ask questions and comment on what they have seen. Here are some questions for discussion:
  • What is the role of genetic counselling?
  • How does Down syndrome occur?  (Here, you can discuss translocation and review meiosis, as needed.)
  • Describe the screening test outlined in the case study.  What are the pros and cons of this blood test?
  • Describe the diagnostic test outlined in the case study.  What are the pros and cons of the amniocentesis?
• The case study could also be used as a preview for a larger project.
  • For example, students may do a research project on Down syndrome or another genetic disorder.