Hemophilia
Curriculum Link > Biology 12
Protein Synthesis
- Explain how mutations in DNA affect protein synthesis
What is the case study about?
In this case study, students will uncover a family’s inheritance pattern of hemophilia. Students will also apply their knowledge of sex-linked inheritance to make predictions in their pedigree analysis.
Using the case study in the classroom
- This case study requires background knowledge of pedigree charts, (sex-linked) inheritance and mutations.
- This case study can be used to enrich the Biology 12 curriculum. It can also be used with the IB (International Baccalaureate) and AP (Advanced Placement) Biology curricula.
- Students can complete the case study independently. This could be carried out as a classroom or homework activity.
- Students can also work in pairs to complete their case study.
- Note: If you are planning to have students complete other case studies found on this website, you can always assign student pairs different cases. This will allow student pairs to focus on their own case study and then learn about the other cases when they are presented by their peers.
- This case study could also be used as a preview activity for a larger project.
- For example, students may do a research project on Hemophilia A or Hemophilia B.
- This case study could also be used as an opportunity to review types of mutations. For example, students could determine the type of genetic mutations that produce the different types of hemophilia. Students could then note similarities and differences that are found in the resultant mutant proteins.
